Description
Product Characteristics:
Aliases: DKFZp434A012 antibody, KIAA0066 antibody, P130 antibody, Rab3 GAP antibody, Rab3 GAP p130 antibody, RAB3 GTPase activating protein 130 kDa subunit antibody, Rab3 GTPase activating protein catalytic subunit antibody, RAB3 GTPase activating protein subunit 1 (catalytic) antibody, RAB3 GTPase-activating protein 130 kDa subunit antibody, Rab3 GTPase-activating protein catalytic subunit antibody, Rab3-GAP antibody, Rab3-GAP p130 antibody, RAB3GAP antibody, rab3gap1 antibody, RAB3GAP130 antibody, RB3GP_HUMAN antibody, WARBM1 antibody
Target Information: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]